U.S., April 22 -- ClinicalTrials.gov registry received information related to the study (NCT07541807) titled 'Assessing Changes in Gadoxetate Metabolism by the Liver Using MRI' on July 08, 2025.
Brief Summary: Identifying drugs at risk of interacting with other drugs, called drug-drug interaction (DDI), early in their development is crucial in avoiding late-stage drug development failures. The liver plays a key role in DDIs , with liver cells playing a major part in the taking up and getting rid of drugs. Currently, there is a lack of safe, widely available tools for testing DDIs in humans, particularly interactions involving liver cell transporters.
This study is part of five work packages under the TRISTAN project (Translational Imaging...