U.S., April 18 -- ClinicalTrials.gov registry received information related to the study (NCT07536763) titled 'Arterial Vascular Effects of Estetrol-drospirenone Combined Oral Contraceptive Pill' on April 12.
Brief Summary: The goals of this clinical trial are to investigate the effect of the estetrol (E4)-drospirenone combined oral contraceptive (COC) pill on flow-mediated dilatation (FMD) of the brachial artery and pulse wave velocity (PWV), in comparison to the ethinylestradiol (EE)-levonorgestrel COC pill, and to compare their respective effects on blood pressure, chronic inflammatory markers, as well as glycaemic and lipid indices.
The main questions it aims to answer are:
Does E4-drospirenone COC have significantly smaller effects t...