U.S., March 12 -- ClinicalTrials.gov registry received information related to the study (NCT07464080) titled 'Advanced Brain Imaging-TKA (fMRI-TKA)' on Jan. 28.

Brief Summary: Knee replacement surgery is a common and effective treatment for pain and mobility loss, yet up to 1 in 5 patients remain dissatisfied after surgery due to ongoing pain or difficulty with daily activities. Currently, clinicians cannot reliably predict which patients will experience these challenges.

This study uses MRI scan of the brain to investigate whether specific patterns of brain activity can predict patient satisfaction after total knee arthroplasty (TKA). By comparing brain networks before surgery and afterward, and linking these changes to patient-reported ...