Clinical Trial: A RCT of Collagen Scaffold for the Repair of Talus Cartilage Injury

U.S., Nov. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07917806) titled 'A RCT of Collagen Scaffold for the Repair of Talus Cartilage Injury' on Aug. 18, 2025.

Brief Summary: The goal of this clinical trial is to test whether adding a collagen protein scaffold can improve cartilage repair of talus injury, compared to standard surgery alone. The study will enroll 40 patients (aged 18-55) with talus cartilage damage who haven't responded to conservative treatments.

The main questions it aims to answer are:

* Does the collagen scaffold help regenerate better-quality cartilage (measured by MRI scans at 3/6 months and 1/2 years)?

* Do patients experience better pain relief and ankle function after this comb...