Clinical Trial: A Pilot Study on the Efficacy of Oral Low Dose Naltrexone for Vulvodynia

U.S., Oct. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07862400) titled 'A Pilot Study on the Efficacy of Oral Low Dose Naltrexone for Vulvodynia' on Oct. 01.

Brief Summary: The goal of this observational pilot study is to assess the safety, efficacy, and tolerability of oral low dose naltrexone (LDN) in the treatment of vulvodynia. The aims it will address are:

Aim 1:To assess the efficacy of LDN by reviewing patient-reported Global Treatment Improvement scale scores after the 4-week treatment period.

Aim 2: To identify the impact on overall and vulvar pain by calculating the difference between average pre- and post-treatment PGIC, NRS, CSI and VPAQ scores.

Aim 3: To identify adverse effects that pati...