Clinical Trial: A Phase I Study of Pazopanib in Combination With Trabectedin, Ipilimumab and Nivolumab (TraPIN) in Pediatric and Young Adult Patients With Recurrent Soft Tissue Sarcomas

U.S., March 4 -- ClinicalTrials.gov registry received information related to the study (NCT07444619) titled 'A Phase I Study of Pazopanib in Combination With Trabectedin, Ipilimumab and Nivolumab (TraPIN) in Pediatric and Young Adult Patients With Recurrent Soft Tissue Sarcomas' on Feb. 26.

Brief Summary: The goal of this study is to build on the experience of the SAINT trial by evaluating the safety and efficacy of the addition of pazopanib to their published chemotherapy regimen.

Study Start Date: Aug. 31, 2026

Study Type: INTERVENTIONAL

Condition: Soft Tissue Sarcomas

Intervention: DRUG: Pazopanib

Given by mouth

DRUG: Trabectedin

Given by IV

DRUG: Ipilimumab

Given by IV

DRUG: Nivolumab

Given by IV

Recruitment Status: NOT_Y...