Clinical Trial: A Phase I First-in-human Trial of Bvax (B-cell Vaccination) in Addition to Standard of Care Chemoradiotherapy for Newly Diagnosed Glioblastoma

U.S., Feb. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07422896) titled 'A Phase I First-in-human Trial of Bvax (B-cell Vaccination) in Addition to Standard of Care Chemoradiotherapy for Newly Diagnosed Glioblastoma' on Jan. 30.

Brief Summary: The objectives of this phase I first-in-human trial are to evaluate safety, feasibility, and preliminary efficacy of an individualized Bvax vaccine in addition to standard of care chemoradiation in patients with newly diagnosed glioblastoma.

Study Start Date: June 01, 2026

Study Type: INTERVENTIONAL

Condition: Glioblastoma

Intervention: BIOLOGICAL: B-cell vaccination

The study treatment includes dose-escalation of B-cell vaccine (Bvax) and a fixed dose of au...