U.S., June 6 -- ClinicalTrials.gov registry received information related to the study (NCT07629960) titled 'A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations' on June 01.
Brief Summary: A first in human study to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of BLU-924 / SAR449336, a pan-KRAS inhibitor, in participants with advanced Pancreatic Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer harboring KRAS mutations.
Study Start Date: June 30
Study Type: INTERVENTIONAL
Condition:
Advanced Solid Tumor
Non-Small Cell Lung Cancer
Colorectal Neoplasms
Pancreatic Ductal Adenocarcinoma
Intervention:
DRUG: BLU-924
Tablet
Recruitment Status: RECRUITING
Spon...