Clinical Trial: A First-in-human Phase I Study to Evaluate EMB-15 in Patients With Locally Advanced or Metastatic Solid Tumors.

U.S., May 27 -- ClinicalTrials.gov registry received information related to the study (NCT07607054) titled 'A First-in-human Phase I Study to Evaluate EMB-15 in Patients With Locally Advanced or Metastatic Solid Tumors.' on May 19.

Brief Summary: The primary purpose of this study is to evaluate safety and tolerability profile of EMB-15, identify the recommended Phase 2 dose(s) (RP2Ds) for EMB-15. Pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity, and the anti-tumor activity of EMB-15 will also be assessed.

Study Start Date: May 26

Study Type: INTERVENTIONAL

Condition: Locally Advanced or Metastatic Solid Tumors

Intervention: BIOLOGICAL: EMB-15

EMB-15 is a recombinant humanized bi-specific antibody against ALPP/ALPG and CD...