India, March 12 -- For travelers who believe the journey should be just as memorable as the destination, Amtrak's Lake Shore Limited route offers one of the most scenic overnight rail trips in the Northeast and Midwest. The roughly 19-hour journey winds past Great Lakes shorelines, historic waterways, and a string of vibrant cities-making the trip an experience in itself rather than simply a method of transportation.

Running daily between Chicago and the East Coast, Amtrak's Lake Shore Limited travels through a geographically diverse stretch of the country. Passengers follow the southern shoreline of Lake Michigan, then head east through the industrial Midwest and into upstate New York, where the route runs parallel to stretches of the M...