Srinagar, Aug. 22 -- Srinagar- The government has restricted the manufacture, sale and distribution of all fixed dose combinations containing Chlorpheniramine Maleate and Phenylephrine Hydrochloride, directing manufacturers to carry a warning that the medicines should not be used in children below four years of age.

The latest notification extends an earlier restriction issued in April 2025 to all formulations containing the two ingredients.

The decision followed recommendations of an expert committee and the Drugs Technical Advisory Board (DTAB), which examined the safety of such combinations for young children.

The government said the use of these combinations may pose risks to children below four years of age and noted that safer al...