India, April 24 -- Washington has imposed sweeping sanctions on a powerful Cambodian lawmaker and his business network, accusing them of orchestrating a vast web of cyber scams that targeted Americans and generated millions of dollars through deception, coercion, and alleged human trafficking.

The US Department of the Treasury announced Thursday that its Office of Foreign Assets Control sanctioned Senator Kok An, along with 28 individuals and entities tied to his operations, in what officials described as one of the most aggressive crackdowns yet on Southeast Asia's expanding scam economy.

According to the Treasury, Kok An, an influential political and business figure, controlled a network of scam compounds across Cambodia that defraud...