New Delhi, July 2 -- Alphabet Inc. (GOOGL) owes €4.125 billion for how it used Android to lock in Google's position across mobile search, and there is nowhere left to appeal.

The Court of Justice of the European Union dismissed Google's final challenge to the Android antitrust fine, confirming a 2022 General Court ruling that had already trimmed the original 2018 penalty from €4.34 billion to its current figure. For Alphabet, the ruling closes a decade-long rearguard action against a case the European Commission opened when Android's global dominance was still being built rather than already entrenched.

The judgment turned in part on a concept the General Court had applied and Google had contested: "status quo bias." Pre-ins...