India, April 12 -- High-stakes talks between the United States and Iran aimed at defusing the ongoing West Asia conflict ended without a breakthrough on Sunday, as delegations from both sides departed Pakistan following a round of historic negotiations.

The dialogue, hosted in Islamabad amid mounting global concerns over energy supply disruptions, marked one of the most direct engagements between Washington and Tehran in recent years. However, key differences - particularly over Iran's nuclear programme - prevented a consensus.

Leading the US delegation, Vice President JD Vance acknowledged that the negotiations failed to produce a peace agreement. He pointed to Tehran's refusal to scale back its nuclear ambitions as a central obstacle....