India, Sept. 28 -- XtalPi Holdings Limited (2228.HK), an AI- and robotics-driven drug and materials discovery company, announced the submission of an Investigational New Drug (IND) application to the U.S. FDA for KQTD-126 for chronic intestinal pain.

The chronic intestinal pain is associated with irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). The company said IBS affects approximately 10% to 15% of the global population, while more than 10 million live with IBD.

Chronic abdominal pain remains a burden for patients with both conditions, including some patients with IBD whose underlying inflammation is controlled with standard therapies.

KQTD-126 is an investigational gut-restricted pan-tropomyosin receptor kinase (pa...