India, July 2 -- A new review published in Brain Medicine suggests that creatine may help some people with depression by improving the brain's energy supply. However, the researchers emphasized that the current evidence is mixed, and more studies are needed before firm conclusions can be made.

For the study, researchers led by Bassam Jeryous Fares at the University of Ottawa reviewed six published reports covering five randomized controlled trials in which participants were randomly assigned to receive either creatine or a placebo, with neither the participants nor the investigators knowing which they received.

The studies were conducted in South Korea, the United States, Brazil, Israel, and India. Altogether, 238 people took part in the ...