India, April 13 -- The major U.S. index futures are currently pointing to a lower open on Monday, with stocks likely to give back ground after turning in a strong performance last week.

Concerns about a re-escalation of the conflict in the Middle East are likely to weigh on Wall Street after weekend talks between the U.S. and Iran failed to produce an agreement.

"They have chosen not to accept our terms," U.S. Vice President JD Vance said in a brief news conference but left open the possibility that terms could still be reached. Iran said that "unreasonable U.S. demands" prevented the progress of the negotiations.

A spike by the price of crude oil is also likely to generate early selling pressure, with crude oil futures jumping back abov...