MUMBAI, India, Sept. 22 -- Intellectual Property India has published a patent application (202617073208 A) filed by Indiana University Research And Technology Corporation on June 12, 2026, for Treatment Of Ulcerative Colitis And Symptoms Thereof.
Inventors include Kelley, Mark R.; and Kapur, Reuben.
The application for the patent was published on September 18, 2026, under issue no. 38/2026.
Abstract: Methods of treating UC and IBD are disclosed herein. Particularly, it has been found that by blocking the redox activity of APE1/Ref-1, the elevated expression of HIF- 1a in HSPCs is inhibited and the dynamics of HSPCs both in normal and Dnmt3a mutant mice under inflammatory milieu of UC is reversed. It has further been found that blocking t...