MUMBAI, India, Oct. 12 -- Intellectual Property India has published a patent application (202617070105 A) filed by Universitat Autnoma De Barcelona; Universitat Pompeu Fabra; and Fundaci Institut Hospital Del Mar D'Investigacions on June 04, 2026, for Smad4 Engineered Cytotoxic Lymphocytes For Cell Therapy.
Inventors include Muntasell Castellvi, Aura; Rea, Anna; and Sanvicente Garca, Marta.
The application for the patent was published on October 09, 2026, under issue no. 41/2026.
Abstract: A modified human cytotoxic lymphocyte cell is provided for adoptive immunotherapy, comprising an inactivating mutation in SMAD4 gene, which renders the cell resistant to the immunosuppressive effects of TGF-ß and allows it to maintain its cytotoxicity....