MUMBAI, India, Nov. 2 -- Intellectual Property India has published a patent application (202617092027 A) filed by Arbor Biotechnologies, Inc. on July 29, 2026, for Methods For Treating Primary Hyperoxaluria Via Genetic Editing Of Hydroxyacid Oxidase 1.
Inventors include Ditommaso, Tia; Kuefner, Michael; Garrity, Anthony; Lin, Paulo Jia Ching; and Tam, Ying K..
The application for the patent was published on October 30, 2026, under issue no. 44/2026.
Abstract: A composition for genetic editing of a hydroxyacid oxidase 1 (HAO1) gene, comprising: (a) a messenger RNA (mRNA) encoding a Cas12i2 polypeptide, (b) a guide RNA (gRNA) targeting the HAO1 gene; and (c) lipid excipients, which optionally form lipid nanoparticles. Also provided herein ...