Intellectual Property India Publishes Patent Application for Interleukin 18 (il-18) Variants And Fusion Proteins Comprising Same

MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202617091095 A) filed by Guidant Biotherapeutics, Inc. on July 27, 2026, for Interleukin 18 (il-18) Variants And Fusion Proteins Comprising Same.

Inventor includes Cini, John K..

The application for the patent was published on October 23, 2026, under issue no. 43/2026.

Abstract: Provided herein are variant human IL-18 (hIL-18) proteins and fusion proteins comprising the variant hIL-18 proteins. Such variant hIL-18 proteins exhibit biological IL-18 activity while having reduced or no detectable binding to inhibitory IL-18BP. Thus, in some embodiments, the variant hIL-18 proteins advantageously retain IL- 18 biological activity in the presence of IL-1...