India, April 2 -- The Government of India has issued a release:
A team of scientists has uncovered a fundamental flaw in a long-standing model of how bacteria control gene expression that can form the base for innovative strategies to combat tuberculosis and other bacterial infections.
Tuberculosis is one of the world's deadliest infectious diseases, and drug-resistant strains pose an increasing global threat to cure of the disease. M. tuberculosis (TB) bacteria survive inside the human host by precisely regulating gene expression under extreme stress conditions.
For years, scientists believed that a protein called σ factor binds RNA polymerase, initiates bacterial transcription and is then released once the enzyme begins elongating...