International Clinical Trial: Upadacitinib in addition to steroids for the initial treatment of acute severe ulcerative colitis (ASUC)

Geneva, July 20 -- International Clinical Trials Registry received information related to the study (ACTRN12626000839303) titled 'Upadacitinib in addition to steroids for the initial treatment of acute severe ulcerative colitis (ASUC)' on July 10.

Study Type: Interventional

Study Design: Purpose: Treatment Allocation: Randomised controlled trial

Primary Sponsor: The University of Melbourne

Condition: acute severe ulcerative colitis acute severe ulcerative colitis Oral and Gastrointestinal - Inflammatory bowel disease

Intervention: Upadacitinib 45mg tablet orally once daily for the first 5 days of admission. This intervention will be in addition to standard of care treatment with intravenous hydrocortisone, which will be administer...