International Clinical Trial: Short-Course Radiotherapy Followed by mFOLFOX6 with Precise Targeted Therapy and PD-1 Inhibition Versus Short-Course Radiotherapy Followed by mFOLFOX6 Alone in High-Risk pMMR/MSS Rectal Adenocarcinoma: A Prospective, Multicenter, Randomized Controlled Phase ? Study (CRIT ? Study)

Geneva, Sept. 25 -- International Clinical Trials Registry received information related to the study (ChiCTR2600132933) titled 'Short-Course Radiotherapy Followed by mFOLFOX6 with Precise Targeted Therapy and PD-1 Inhibition Versus Short-Course Radiotherapy Followed by mFOLFOX6 Alone in High-Risk pMMR/MSS Rectal Adenocarcinoma: A Prospective, Multicenter, Randomized Controlled Phase ? Study (CRIT ? Study)' on Sept. 20.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: The Sixth Affiliated Hospital , Sun Yat-sen University

Condition: Patients with high-risk, pMMR/MSS, locally advanced rectal cancer

Intervention: Trial group:Sequential mFOLFOX6 chemotherapy for 6 cycles after SCRT, combined with precision ...