International Clinical Trial: Prospective, Single-Arm, Exploratory Study of Retlirafusp Alpha Combined with CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal Cancer

Geneva, April 20 -- International Clinical Trials Registry received information related to the study (ChiCTR2600122304) titled 'Prospective, Single-Arm, Exploratory Study of Retlirafusp Alpha Combined with CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal Cancer' on April 11.

Study Type: Interventional study

Study Design: Single arm

Primary Sponsor: Xijing Hospital, Air Force Medical University

Condition: locally advanced rectal cancer

Intervention: Trial Group:Rilavapu a injection (1800mg, intravenous infusion, Q3W) combined with CAPOX regimen (Oxaliplatin 130mg/m2, Day 1 Capecitabine 1000mg/m2, Days 1-14), 4 cycles preoperatively

Recruitment Status: Not Recruiting

Phase: 2

Date of First Enrollment: 2026-04-13

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