International Clinical Trial: Esmolol to Reduce Severe Pain After Nerve Block in Knee Replacement Patients

Geneva, Aug. 6 -- International Clinical Trials Registry received information related to the study (ChiCTR2600129126) titled 'Esmolol to Reduce Severe Pain After Nerve Block in Knee Replacement Patients' on July 31.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Fujian Medical University Union Hospital

Condition: Rebound Pain After Peripheral Nerve Block

Intervention: Experimental group:Intravenous infusion of esmolol will be initiated 5 minutes before skin incision and maintained at 10 µg/kg/min until the completion of surgical skin closure.

Recruitment Status: Not Recruiting

Phase: 4

Date of First Enrollment: 2026-08-01

Target Sample Size: Experimental group:70;Control group:70;

Countries ...