International Clinical Trial: Effect of prophylactic ondansetron on hemodynamic changes in elderly patients following spinal anesthesia: A Randomized Controlled Trial

Geneva, April 28 -- International Clinical Trials Registry received information related to the study (TCTR20260416008) titled 'Effect of prophylactic ondansetron on hemodynamic changes in elderly patients following spinal anesthesia: A Randomized Controlled Trial' on April 16.

Study Type: Interventional

Study Design: Randomized

Primary Sponsor: N/A

Condition: Hypotension and bradycardia are common complications following spinal anesthesia, particularly in elderly patients with increased cardiovascular vulnerability. Ondansetron, a 5HT3 receptor antagonist, has been suggested to attenuate these effects by inhibiting the Bezold Jarisch reflex, a key mechanism underlying spinal anesthesia induced hypotension. Ondansetron Spinal anesth...