International Clinical Trial: A single-center, randomized, double-blind, dose-finding, normal saline-controlled clinical trial to evaluate the safety and efficacy of recombinant type III humanized collagen lyophilized fiber (Colnet) in improving moderate to severe perioral wrinkles

Geneva, March 20 -- International Clinical Trials Registry received information related to the study (ChiCTR2600119404) titled 'A single-center, randomized, double-blind, dose-finding, normal saline-controlled clinical trial to evaluate the safety and efficacy of recombinant type III humanized collagen lyophilized fiber (Colnet) in improving moderate to severe perioral wrinkles' on Feb. 26.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Beijing Tiantan Hospital, Capital Medical University

Condition: Perioral wrinkles

Intervention: Low-dose Collagen Group:Recombinant type III humanized collagen lyophilized fiber (Colnet) 12mg + normal saline 3ml, formulated to 4mg/ml, linear retrograde injection into dermi...