International Clinical Trial: A Phase I Clinical Trial to Evaluate CMS-D017 Following Single and Multiple Doses in Healthy Participants

Geneva, March 20 -- International Clinical Trials Registry received information related to the study (ChiCTR2600119300) titled 'A Phase I Clinical Trial to Evaluate CMS-D017 Following Single and Multiple Doses in Healthy Participants' on Feb. 25.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Peking University Third Hospital

Condition: Paroxysmal nocturnal hemoglobinuria

Intervention: SAD stage CMS-D017 group:Six dose groups (50 mg, 100 mg, 200 mg, 400 mg, 800 mg and 1200 mg) were taken orally on an empty stomach. SAD stage placebo group:Six dose groups (50 mg, 100 mg, 200 mg, 400 mg, 800 mg and 1200 mg) were taken orally on an empty stomach. MAD stage CMS-D017 group:Four dose groups (50 mg BID, 100 mg BI...