U.S., March 18 -- ClinicalTrials.gov registry received information related to the study (NCT07475910) titled 'Venous Thromboembolism and Chronic Pain After Major Limb Trauma: A Prospective Cohort Study' on March 13.
Brief Summary: Major limb trauma is associated with a high risk of venous thromboembolism (VTE) due to systemic inflammation, endothelial injury, immobilization, and hypercoagulability. While VTE is commonly studied as a short-term complication affecting morbidity and mortality, its potential relationship with long-term pain outcomes after trauma has not been well investigated.
This prospective observational cohort study aims to evaluate whether objectively confirmed VTE is associated with an increased risk of persistent clini...