U.S., April 14 -- ClinicalTrials.gov registry received information related to the study (NCT07523191) titled 'Validation of Presence-IP1.0 for Detection of Consciousness Using Reduced-Montage TMS-EEG' on April 03.

Brief Summary: This study aims to validate a novel real-time algorithm (Presence-IP1.0) designed to detect consciousness from TMS-evoked EEG responses using a reduced electrode montage. Thirty healthy adult participants will undergo TMS-EEG recordings during wakefulness and sleep. The algorithm's ability to differentiate conscious from unconscious states will be evaluated against behavioral and physiological state classification. The goal is to determine whether Presence-IP1.0 achieves clinically useful accuracy for detecting con...