U.S., May 23 -- ClinicalTrials.gov registry received information related to the study (NCT07603375) titled 'Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma' on May 18.
Brief Summary: The goal of this trial is to learn if adding consolidative chemotherapy to routine chemoradiation can better control both local recurrence and metastasis and reduce the need for surgical intervention.
Study Start Date: Aug. 01, 2026
Study Type: INTERVENTIONAL
Condition:
Esophageal Adenocarcinoma
Intervention:
DRUG: FOLFOX (5-fluorouracil, Leucovorin, Oxaliplatin)
modified-FOLFOX-6 or FLOT
Recruitment Status: NOT_YET_RECRUITING
Sponsor: Duke University
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