U.S., April 15 -- ClinicalTrials.gov registry received information related to the study (NCT07529639) titled 'Tumor Budding and T1 Substaging in Urothelial Bladder Cancer' on April 08.
Brief Summary: Bladder cancer is a significant global and local health concern, and predicting how aggressive a patient's tumor will behave is critical for guiding treatment. This observational study aims to evaluate two specific microscopic features of urothelial bladder carcinoma to see if they can reliably predict patient outcomes: the depth of early tumor invasion (T1 substaging) and the presence of small clusters of cancer cells at the tumor's edge (Tumor Budding).
Researchers will retrospectively analyze tissue samples (paraffin blocks) from at least ...