U.S., June 27 -- ClinicalTrials.gov registry received information related to the study (NCT07672275) titled 'Transfusion-Related Changes in Oxidative Stress Biomarkers in Neonates' on Dec. 15, 2025.
Brief Summary: Reactive oxygen species (ROS), which include peroxides, are generated in the human body as by-products of cellular metabolism. In small amounts, they fulfill important physiological functions. However, when produced in excess, they can damage cells and tissues. Extremely low gestation age neonates (ELGANs) are particularly vulnerable to such harmful effects because their antioxidant defense systems are immature, and they are exposed to increased ROS levels due to the oxygen therapy required after birth.
Fetal hemoglobin (HbF), t...