U.S., June 24 -- ClinicalTrials.gov registry received information related to the study (NCT07662083) titled 'Trans Auricular Vagal Nerve Stimulation in Patients With IBS-C' on June 17.
Brief Summary: This study evaluates the efficacy and safety of transcutaneous auricular vagus nerve stimulation (ta-VNS) in adults with constipation-predominant irritable bowel syndrome (IBS-C). Participants will be randomized to receive either active or sham stimulation using a non-invasive auricular device over a 60-day period.
The primary objectives are to assess changes in symptom severity and quality of life using validated instruments, including the IBS Symptom Severity Scale (IBS-SSS) and the IBS Quality of Life questionnaire (IBS-QOL). Secondary ass...