U.S., May 13 -- ClinicalTrials.gov registry received information related to the study (NCT07581457) titled 'Tranexamic Acid in Pediatric Idiopathic Scoliosis Surgery' on May 06.
Brief Summary: This study will evaluate whether tranexamic acid (TXA), a medication used to reduce bleeding, is effective and safe in children undergoing surgery for idiopathic scoliosis. Significant blood loss is common during this type of surgery and often requires blood transfusions.
Participants will be randomly assigned to one of three groups: (1) TXA given as an intravenous bolus followed by continuous infusion, (2) TXA given as two intravenous bolus doses, or (3) placebo (saline). Neither the patients nor the medical team will know which treatment is given....