U.S., July 25 -- ClinicalTrials.gov registry received information related to the study (NCT07725107) titled 'Topical Oxygen Therapy for BRONJ' on July 21.
Brief Summary: A randomized clinical trial comparing Blue(R)m oral gel and autologous PRF membrane as adjuncts to surgical debridement in BRONJ/MRONJ patients.
Study Start Date: April 01
Study Type: INTERVENTIONAL
Condition:
Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ)
Oxygen
Topical Administration
Wound Healing
Intervention:
PROCEDURE: Topical Blue(R)m application
Intraoperative application of Blue(R)m oral gel to the debrided surgical site before primary closure
PROCEDURE: PRF membrane placement
Intraoperative placement of an autologous PRF membrane over the debrid...