Clinical Trial: Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies

U.S., May 5 -- ClinicalTrials.gov registry received information related to the study (NCT07565220) titled 'Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies' on April 27.

Brief Summary: This phase 1 trial will investigate the safety and effectiveness of Thiotepa, Busulfan, and Fludarabine (TBF) conditioning regimen with post-transplant cyclophosphamide (PTCy) in HLA-matched related or unrelated donor allogeneic stem cell transplantation (alloSCT).

Study Start Date: June 01

Study Type: INTERVENTIONAL

Condition: Acute Lymphocytic Leukemia (ALL) Acute Myeloid Leukemia (AML) Acute Leukemia Myelodysplastic Syndrome(MDS) High-risk Myeloprolif...