Clinical Trial: The Use of Two Bone Substitutes in Adjunct to EMD for the Treatment of One- and Two-wall Intrabony Defects.

U.S., April 23 -- ClinicalTrials.gov registry received information related to the study (NCT07546279) titled 'The Use of Two Bone Substitutes in Adjunct to EMD for the Treatment of One- and Two-wall Intrabony Defects.' on Dec. 17, 2025.

Brief Summary: The main aim will be to evaluate the difference in PD changes at 12-month follow-up, measured from the gingival margin to the base of the pocket, comparing periodontal regeneration using two different bone substitutes, that is bovine derived xenograft granules (BioOss(R) Collagen) and one resorbable sponge-like hydroxyapatite collagen matrix (OssixTM Bone), in adjunct with EMD after microsurgical flap elevation.

Inclusion criteria I. Men and women over or equal to the age of 18 years II. Pat...