Clinical Trial: The Role of Brain Lactate Metabolism in Neuroprotection During Healthy Aging

U.S., July 29 -- ClinicalTrials.gov registry received information related to the study (NCT07731451) titled 'The Role of Brain Lactate Metabolism in Neuroprotection During Healthy Aging' on July 16.

Brief Summary: The brain's primary source of fuel is glucose. Unfortunately, the brain's ability to use glucose declines during normal aging. This decline in brain glucose metabolism makes it vulnerable to cognitive impairment and Alzheimer's disease. The brain can use another fuel source - lactate - which becomes available to the brain during exercise. The investigators have discovered that when lactate fuels the brain, brain glucose metabolism also improves. Essentially, from a metabolic angle, the brain appears younger. Recently, the investi...