U.S., Oct. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07902440) titled 'The Impact of Proton-pump Inhibitors on Threshold Dose Distributions' on Aug. 10, 2016.
Brief Summary: Background and Rationale:
Antacids might influence the structure/degradation and therefore the allergenicity of food proteins. This study intends to perform double-blind placebo-controlled food challenges in walnut allergic patient to determine threshold dose distribution curves and to investigate the impact of antacids (proton-pump inhibitors) on the allergy eliciting dose of walnut and the severity of the clinical manifestation in walnut allergic patients.
Objectives:
Investigation of effect of Omeprazole on the threshold dose...