Clinical Trial: The Effect of Preoperative Administration of Oral Tizanidine on the Postoperative Pain and Sleep Quality

U.S., Sept. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07800364) titled 'The Effect of Preoperative Administration of Oral Tizanidine on the Postoperative Pain and Sleep Quality' on Aug. 29.

Brief Summary: The majority of lower limb fractures treated with surgery often leading to significant morbidity and mortality. Despite improvements in perioperative care, about 20% suffer from severe postoperative complications. So, effective perioperative pain management is crucial in this demographic to ensure optimal recovery and reduce complications. (1) Controlling the postoperative pain often begins in recovery room by using opioids, especially morphine. However, systemic opioids may develop many complications ...