U.S., May 20 -- ClinicalTrials.gov registry received information related to the study (NCT07597486) titled 'The Effect of Intraoperative Esketamine Infusion on Pruritus in Elderly Surgical Patients' on May 07.

Brief Summary: To explore the effect of intraoperative esketamine on pruritus in elderly patients undergoing elective general anesthesia for knee replacement surgery

Study Start Date: May 15

Study Type: INTERVENTIONAL

Condition: Senile Pruritus

Intervention: DRUG: Esketamine

Esketamine 0.2 mg/kg is intravenously administered 30 minutes prior to the completion of the operation.

DRUG: Normal Saline

An equal volume of normal saline is intravenously administered 30 minutes prior to the completion of the operation.

Recruitment S...