Clinical Trial: taVNS in Veterans With Knee OA (AVAHCS)

U.S., Sept. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07804199) titled 'taVNS in Veterans With Knee OA (AVAHCS)' on Aug. 21.

Brief Summary: The objectives of this study are to identify an optimal transcutaneous auricular vagus nerve stimulation (taVNS) dosing regimen for pain relief and anti-inflammatory effects in Veterans with knee osteoarthritis (OA), compared to corticosteroid injection (CSI), and lay the groundwork for future combinatorial therapies with cell-based approaches. The population for this study is Veterans with osteoarthritis (OA). This single-center, randomized pilot study will enroll participants with knee OA, who will be allocated to CSI (n=10), high-dose taVNS (n=15; 1-2 hours/day, ...