U.S., Oct. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07871487) titled 'Tau Pathology in the Brain After Hip or Knee Replacement Surgery' on Oct. 06.
Brief Summary: The goal of this observational study is to study whether major surgery is linked to changes in the brain that are typical of Alzheimer's disease.
The study is a prospective observational study that will be carried out in Uppsala University Hospital. Adults aged 55-75 years who are healthy otherwise (ASA1) having a hip or knee replacement under spinal anesthesia, and a comparison group of people of the same age and sex with hip or knee arthrosis who are not having surgery will be included.
The main questions it aims to answer are:
* Does t...