Clinical Trial: Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder

U.S., May 19 -- ClinicalTrials.gov registry received information related to the study (NCT07593222) titled 'Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder' on April 19.

Brief Summary: Many people with depression do not get better with standard treatments like medications or talk therapy. Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation treatment that uses magnetic pulses to stimulate areas of the brain involved in depression. One form of TMS called intermittent theta burst stimulation (iTBS) is FDA-cleared for depression and takes only 3 minutes to deliver. However, about one-third of patients do not respond to iTBS, and another one-third do not reach full remission. Imp...