U.S., Sept. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07829718) titled 'Suzetrigine (Journavx) for Pain Management After Spine Surgery' on Sept. 14.
Brief Summary: This prospective, single-center interventional study will evaluate the effect of suzetrigine (Journavx), a selective NaV1.8 inhibitor, on postoperative opioid requirements in patients undergoing spine surgery. Participants receiving suzetrigine as part of standard perioperative care will be compared with matched historical controls treated with standard multimodal analgesia. The study aims to characterize the magnitude and variability of opioid-sparing effects during the immediate postoperative period, with primary assessment focused on inpa...