Clinical Trial: Study on Cutoff Revision Effects and Evaluation of NNT in Primary Aldosteronism

U.S., June 3 -- ClinicalTrials.gov registry received information related to the study (NCT07621458) titled 'Study on Cutoff Revision Effects and Evaluation of NNT in Primary Aldosteronism' on May 21.

Brief Summary: The goal of this observational study is to evaluate the real-world impact of applying the revised aldosterone-to-renin ratio (ARR) cutoff recommended in the 2025 primary aldosteronism guideline in adults with hypertension and biochemical findings suggestive of an intermediate probability of lateralizing primary aldosteronism (PA). The main questions it aims to answer are:

* What is the number needed to test (NNT) to diagnose one case of primary aldosteronism when using the revised ARR cutoff (>20)?

* What is the optimal ARR cu...