Clinical Trial: Spinal Cord Stimulation for Refractory Pain Randomized Controlled Trial: the PAcStim RCT

U.S., March 13 -- ClinicalTrials.gov registry received information related to the study (NCT07468591) titled 'Spinal Cord Stimulation for Refractory Pain Randomized Controlled Trial: the PAcStim RCT' on Feb. 26.

Brief Summary: Neuropathic pain affects 6-10% of the global population and is poorly managed - current drug treatments succeed in only ~25% of patients. Spinal cord stimulation (SCS) modulates pain by electrically stimulating spinal dorsal column fibres. The newer paresthesia-free mode (PF-SCS, 500-10,000 Hz) appears more effective and tolerable than traditional paresthesia-based SCS, with superior outcomes shown in the SENZA-RCT. All promising PF-SCS studies have been unblinded, making them susceptible to placebo effects. The one ...