U.S., Sept. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07847333) titled 'Sonic Irrigation Activation for Postoperative Pain After Root Canal Treatment' on Sept. 20.

Brief Summary: This randomized controlled clinical trial will evaluate whether sonic activation of the root canal irrigant using the EndoActivator system reduces postoperative pain after root canal treatment compared with conventional syringe irrigation.

Adults aged 18 to 60 years with pulp necrosis and asymptomatic apical periodontitis involving restorable permanent single-rooted premolars will be eligible to participate. A total of 176 participants will be randomly assigned in a 1:1 ratio to either conventional syringe irrigation or sonic...